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Interstate 64 (I-64) in the U.S. state of Illinois is a major east\west Interstate highway that runs through southern Illinois from the St. Louis metropolitan area east to the Indiana state line near Grayville, Illinois. It travels a distance of 130.4 miles (209.9 km)....Full Wikipedia Topic
Highway I-64 runs West to East with exit numbers starting at the western most exit of each state or province.
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